The Gunners were gifted the lead when Hull's David Meyler set up Olivier Giroud to slot home.

Aaron Ramsey almost scored an own goal to let Hull back in but Giroud volleyed in to extend Arsenal's lead.

Theo Walcott wrapped up the victory for the holders when he side-footed in and then rifled in a late shot.

Giroud and Walcott back in groove

Giroud celebrated the birth of his baby boy on Monday and manager Arsene Wenger hoped it would inspire him to break his 11-game scoring drought.

The France striker was restored to the starting line-up, along with fellow forward Walcott, but the pair initially struggled against Hull, who had not conceded in six previous home games.

The Tigers were employing a three centre-back formation and rarely looked like being breached until Meyler's mistake allowed Giroud to slot in his first goal since 13 January.

Walcott's form has also been a concern and, although he looked short of confidence, he set up Giroud's second before looking like his former self when his late double gave him his first goals in five games.

Despite a return to winning ways for manager Arsene Wenger's side, some Gunners fans held up a banner reading 'Arsene, thanks for the memories but it's time to say goodbye'.

Arsenal's injury troubles mount

The priority for both of these teams are their league campaigns as Arsenal remain in the hunt for the Premier League title, while Hull are challenging for promotion from the Championship.

The home side made seven changes and the Gunners six, with the visitors forced into more of a reshuffle when centre-back Per Mertesacker went off injured early on after a clash of heads with Nick Powell.

Arsenal were playing their sixth game in 18 days and, with centre-back Laurent Koscielny already sidelined, the exit of fellow defender Gabriel in the second half has provided the Gunners with problems at the heart of their defence.

Gabriel's replacement in midfielder Aaron Ramsey lasted only 16 minutes before an apparent shoulder injury ended his participation and Arsenal boss Arsene Wenger now faces a selection dilemma against Watford on Sunday.

His side may be attempting to win a third successive FA Cup but, after their last-eight tie, they will attempt an unlikely Champions League comeback from 2-0 down at Barcelona before returning to league action.

Hull goalscoring struggles continue

Hull's main threat came from set-pieces, with one particular free-kick causing panic in the Arsenal area before David Meyler forced keeper David Ospina into a smart save.

Powell's effort from the rebound was parried and Ahmed Elmohamady slotted in, but the assistant referee had already flagged for an offside decision Hull may feel aggrieved by.

However, Hull failed to capitalise on Arsenal's problems at the back and when a rare chance came their way striker Mohamed Diame sent a header wide from eight yards.

Indeed, the closest the home side came was when Ramsey sent a header wide of his own goal and Steve Bruce's men have now scored only once in six games.

Man of the match - Olivier Giroud

Arsenal manager Arsene Wenger speaking to BT Sport: "It was a shock as we lost our two centre-backs in the game and then we lost Aaron Ramsey.

"Mertesacker is not serious, just a little concussion, and I think Gabriel looks all right but for Ramsey I am little bit more concerned.

"It's a thigh injury, but apart from that we have played well."

Hull boss Steve Bruce: "I don't think it's a fair reflection. We've given away two awful goals.

"The one on the first half is one of those horrible ones and when you play against Arsenal - one of the top teams - or anybody for that matter then you cannot give goals away like that."

The stats you need to know

Arsenal scored with their first shot on target in this match - the third successive game that they have done this.

Arsenal have never lost an away FA Cup match against lower league opposition under Arsene Wenger (W12 D4)

The Gunners have won each of their last six visits to Hull in all competitions, scoring at least twice on each occasion.

Hull conceded three or more goals in a competitive home game for the first time since Arsenal won 3-1 there in the Premier League in May 2015.

What next?

Arsenal host Watford on Sunday before trips to Barcelona in the Champions League on 16 March and Everton in the Premier League on 19 March. Hull get back to Championship action when they host MK Dons on Saturday.

(BBC)